Who can join the TRAILBLAZER-ALZ Study?

You may be able to take part in theTRAILBLAZER-ALZ Study if you:

  • are 60–85 years of age
  • have had memory loss for 6 months or more that has become gradually worse over time 
  • have a family member or close friend who is with you at least 10 hours per week and can attend study appointments with you.

What investigational drugs are being studied?

For people with Alzheimer’s disease, an unwanted substance called “beta-amyloid” (or “β-amyloid”) builds up in the brain. The TRAILBLAZER-ALZ research study will examine if investigational drug A can remove β-amyloid, and if investigational drug B can stop it from forming. Some participants in the TRAILBLAZER-ALZ Study will get both of these drugs. This is a novel approach, because it will be the first time researchers have looked at these 2 investigational drugs together. Researchers want to investigate if using both drugs together might work better than using just one. 

What will the TRAILBLAZER-ALZ research study involve?

The study will last for up to 2 years and 5 months, and you will have up to 26 study appointments. To join this study, you will need a study partner. Your study partner can be a family member or close friend who is with you at least 10 hours per week, can attend all study appointments with you, and can tell the research team about any changes in your memory.

Is there a cost to participate?

There is no cost to participate. Participants will receive all study-related care from a research doctor at no cost, and may be compensated per study site visit for time and travel expenses.

Will I be compensated for time and travel?

Volunteers who take part in the study may be compensated per study site visit for time and travel expenses. You can discuss this with the research team.

What else do I need to consider?

The research team will be able to explain more about what the TRAILBLAZER-ALZ Study will involve and it is up to you to decide if you want to take part. Participation in this study is voluntary. Whether or not you decide to participate in this study will not affect your current or future relationships with your doctors. If you decide to participate, you are free to withdraw at any time without affecting those relationships.